Vitiligo Research
In this page we shall discuss some latest research about skin condition vitiligo.
Research about the Chickpeas as vitiligo treatment
A research published on times of India says Chickpeas is very useful in vitiligo treatment. This research conducted by scientists of the Banaras Hindu University (BHU).
For experiment chickpeas cream first applied on 50 patients of vitiligo for 20 to 90 days and patients gain pigmentation on affected parts.
How chickpea is work against depigmentation in this regard researcher say that Amino acids found in chickpeas boost up the production of melanocytes cells, regenerates the pigment cells and hence by increasing the production of melanin handle this chronic vitiligo disease.
Vitiligo and other Auto-immune disorders
There is a close relation between vitiligo and other disorder causes by auto-immunity.
A research published in guardian.co.uk says people suffering from vitiligo are more likely to get underactive thyroid and Addison’s disease etc.
Antibody and Tyrosinase
Serum antibodies cause cytotoxicity and destruction of melanocytes. Also an study suggest that a enzyme called tyrosinase produce melanin (coloring substance) for skin. The autoantibody bind to this enzyme of skin.
Inactive melanocytes work for repigmentation
According to this study there are two types of melanocytes active and inactive. In case of vitiligo active melanocytes are completely missed whereas inactive are present but not affected. Further more study says that in normal skin active melanocytes are present in skin whereas inactive goes to the outer root sheaths of normal hair follicles. Treatment tends to move these inactive melanocytes to the near by epidermis. During this movement Melanocytes change their stats from inactive to active phase. So these inactive melanocytes work for the re-pigmentation in skin.
Compaison of UVB narrow band treawtment and PUVA
Use of uv light therapy for the treatment of different diseases is latest trend in medical science. Two types of uv radiation uvb and uva are frequently applied regarding this purpose.
PUVA is psoralens and uva light based treatment option. In an study when uvb NB and PUVA are applied to treat skin condition vitiligo. It has been proved that uvb NB is relatively better treatment for skin condition vitiligo.
In this study author compare two thing, the percentage of affected area recover by the therapies and color match of repigmented and normal skin.
But further case studies suggest that PUVA is more safe treatment of vitiligo. Whereas a risk of skin cancer is associated with UVB light
Black pepper as pigmentation booster
Very famous research now a days bu Kings’College of London research team.
Piperine found in common kitchen spices black pepper, has been proved an important thing for repigmentation of vitiligo skin problem.
Researcher Professor Antony Young said: that topical treatment with piperine stimulate even pigmentation in the skin.
“Combining this with UVR significantly enhances the pigmentation with results that are cosmetically better than conventional vitiligo therapies.”
Vitiligo and genetics
As it is indicated by several studies that a gene encoding cytotoxic T lymphocyte antigen 4 (CTLA4) has a role in many auto immune diseases. Most expert consider it is also associated with vitiligo but a latest study reveals that there is a week relation between vitiligo and CTLA4. Where as many authorized body suggest that a NALP 1 gene is responsible for vitiligo.





